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Dr Linda Rieswijk, Ph.D. (L.)

Key publications
Phillips, R. V., Rieswijk, L., Hubbard, A. E., Vermeulen, R., Zhang, J., Hu, W., Li, L., Bassig, B. A., Wong, J. Y. Y., Reiss, B., Huang, Y., Wen, C., Purdue, M., Tang, X., Zhang, L., Smith, M. T., Rothman, N., & Lan, Q. (2019). Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer. Epigenetics, 14(11), 1112-1124. https://doi.org/10.1080/15592294.2019.1633866
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Luderer, U., Eskenazi, B., Hauser, R., Korach, K. S., McHale, C. M., Moran, F., Rieswijk, L., Solomon, G., Udagawa, O., Zhang, L., Zlatnik, M., Zeise, L., & Smith, M. T. (2019). Proposed Key Characteristics of Female Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Data in Hazard Assessment. Environmental Health Perspectives, 127(7), Article 075001. https://doi.org/10.1289/EHP4971
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AstraZeneca-Sanger Drug Combination DREAM Consortium (2019). Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications, 10(1), Article 2674. https://doi.org/10.1038/s41467-019-09799-2
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Guyton, K. Z., Rieswijk, L., Wang, A., Chiu, W. A., & Smith, M. T. (2018). Key Characteristics Approach to Carcinogenic Hazard Identification. Chemical Research in Toxicology, 31(12), 1290-1292. https://doi.org/10.1021/acs.chemrestox.8b00321
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Nymark, P., Rieswijk, L., Ehrhart, F., Jeliazkova, N., Tsiliki, G., Sarimveis, H., Evelo, C. T., Hongisto, V., Kohonen, P., Willighagen, E., & Grafstrom, R. C. (2018). A Data Fusion Pipeline for Generating and Enriching Adverse Outcome Pathway Descriptions. Toxicological Sciences, 162(1), 264-275. https://doi.org/10.1093/toxsci/kfx252
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Moodley, K., Rieswijk, L., Oprea, T. I., & Dumontier, M. (2017). Assessing the quality of manually curated drug indication and usage information via ontology term mappings. Paper presented at Bio-Ontologies, Prague, Czech Republic.
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Rieswijk, L., Brauers, K. J. J., Coonen, M. L. J., Jennen, D. G. J., van Breda, S. G. J., & Kleinjans, J. C. S. (2016). Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity. Mutagenesis, 31(5), 603-615. https://doi.org/10.1093/mutage/gew027
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Rieswijk, L., Claessen, S. M. H., Bekers, O., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T., Kleinjans, J. C. S., & van Breda, S. G. J. (2016). Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma. Toxicology, 350, 31-39. https://doi.org/10.1016/j.tox.2016.05.002
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Rieswijk, L. (2016). MicroRNAs and epigenetics in chemical carcinogenesis : an integrative toxicogenomics-based approach. [Doctoral Thesis, Maastricht University]. Uitgeverij BOXPress. https://doi.org/10.26481/dis.20160120lr
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Rieswijk, L., Brauers, K. J. J., Coonen, M. L. J., Van Breda, S. G. J., Jennen, D. G. J., & Kleinjans, J. C. S. (2015). Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes. Mutagenesis, 30(6), 771-784. https://doi.org/10.1093/mutage/gev036
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Recent publications
  • Urovi, V., Celebi, R., Sun, C., Rieswijk, L., Erard, M., Yilmaz, A., Moodley, K., Kumar, P., & Dumontier, M. (2023). TAPS Responsibility Matrix: A tool for responsible data science by design. (pp. 2302.01041v1). https://doi.org/10.48550/arXiv.2302.01041
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  • Miller, R., Muraru, S., Malpartida, A. B., Low, J., de Almeida, M. P., van Engelen, B., Godynyuk, E., Abecassis, B. S., Willighagen, E., Evelo, C., & Rieswijk, L. (2022). An approach to the proposal of drug combination for cancer therapy using a pathway data connectivity approach. ChemRxiv https://doi.org/10.26434/chemrxiv-2022-0n8fp
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  • Rana, I., Rieswijk, L., Steinmaus, C., & Zhang, L. (2021). Formaldehyde and Brain Disorders: A Meta-Analysis and Bioinformatics Approach. Neurotoxicity Research, 39(3), 924-948. https://doi.org/10.1007/s12640-020-00320-y
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  • Moodley, K., Rieswijk, L., Oprea, T. I., & Dumontier, M. (2021). InContext: curation of medical context for drug indications. Journal of biomedical semantics, 12(1), Article 2. https://doi.org/10.1186/s13326-021-00234-4
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  • Smith, M. T., Guyton, K. Z., Kleinstreuer, N., Borrel, A., Cardenas, A., Chiu, W. A., Felsher, D. W., Gibbons, C. F., Goodson, W. H., Houck, K. A., Kane, A., La Merrill, M. A., Lebrec, H., Lowe, L., McHale, C. M., Minocherhomji, S., Rieswijk, L., Sandy, M. S., Sone, H., ... Fielden, M. (2020). The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them. Cancer Epidemiology Biomarkers & Prevention, 29(10), 1887-1903. https://doi.org/10.1158/1055-9965.epi-19-1346
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  • Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y.-C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I.-S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., ... Rieswijk, L. (2020). Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women. Genomics, 112(2), 1223-1232. https://doi.org/10.1016/j.ygeno.2019.07.008
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  • Castriota, F., Rieswijk, L., Dahlberg, S., La Merrill, M. A., Steinmaus, C., Smith, M. T., & Wang, J.-C. (2020). A State-of-the-Science Review of Arsenic's Effects on Glucose Homeostasis in Experimental Models. Environmental Health Perspectives, 128(1), Article 016001. https://doi.org/10.1289/EHP4517
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  • La Merrill, M. A., Vandenberg, L. N., Smith, M. T., Goodson, W., Browne, P., Patisaul, H. B., Guyton, K. Z., Kortenkamp, A., Cogliano, V. J., Woodruff, T. J., Rieswijk, L., Sone, H., Korach, K. S., Gore, A. C., Zeise, L., & Zoeller, R. T. (2020). Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nature Reviews Endocrinology, 16(1), 45-57. https://doi.org/10.1038/s41574-019-0273-8
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  • Phillips, R. V., Rieswijk, L., Hubbard, A. E., Vermeulen, R., Zhang, J., Hu, W., Li, L., Bassig, B. A., Wong, J. Y. Y., Reiss, B., Huang, Y., Wen, C., Purdue, M., Tang, X., Zhang, L., Smith, M. T., Rothman, N., & Lan, Q. (2019). Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer. Epigenetics, 14(11), 1112-1124. https://doi.org/10.1080/15592294.2019.1633866
    More information about this publication
  • Luderer, U., Eskenazi, B., Hauser, R., Korach, K. S., McHale, C. M., Moran, F., Rieswijk, L., Solomon, G., Udagawa, O., Zhang, L., Zlatnik, M., Zeise, L., & Smith, M. T. (2019). Proposed Key Characteristics of Female Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Data in Hazard Assessment. Environmental Health Perspectives, 127(7), Article 075001. https://doi.org/10.1289/EHP4971
    More information about this publication
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For publications see my ORCID profile http://orcid.org/0000-0002-6106-1347

https://www.researchgate.net/profile/Linda_Rieswijk https://independent.academia.edu/LRieswijk