Tackling the Novel Coronavirus

COVID-19 related (research) initiatives

Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal

COVID-19 prediction models

CAPHRI (Laure Wynants, Luc Smits) and a group of international researchers studied 31 prediction models for the early detection and progression of COVID-19 and concluded that most models are not scientifically reliable enough to serve as a basis for medical decision. The systemic review was published in the BMJ. This review will be regularly updated in the coming months:  https://www.bmj.com/content/369/bmj.m1328

Also read the interview with Laure Wynants (CAPHRI) and Maarten van Smeden (UMC Utrecht) here

For more information, please contact dr. Laure Wynants.

COVID-19 Epidemiology update

Systematic reviews

Four Dutch institutes - Maastricht University/CAPHRI, RIVM, Cochrane Netherlands and UMC Utrecht - have joined forces to coordinate new systematic reviews on COVID-19 initiatives within the Netherlands and coordinate them as much as possible to avoid duplication. To date, 50 epidemiologists have signed up to participate in the collection, assessment and, where necessary, summarization of the available data and evidence regarding COVID-19. The systematic reviews will cover the following domains: 1) (curative) interventions; 2) preventive interventions/measures; 3) diagnostic and prognostic prediction models; 4) risk factors and 5) diagnostic tests.

For more information please contact prof. Maurice Zeegers.

COVID-19 and the impact on (the care for) older people


At the request of Ministry of Health (VWS), the Living Lab in Ageing and Long-Term Care started an inventory, together with other academic livings labs for care for the elderly in the Netherlands, into the consequences of the virus in long-term care. Within our research program (via Prof. Dr. Jos Schols), we are working on a national registry initiated by Verenso (the Dutch Association of Elderly Care Physicians) and UNO-VUMC to gain insight into the incidence and course of (suspected) COVID-19 in nursing home care. This way we try to get answers to questions such as: What are the characteristics and symptoms of residents with a (suspected) COVID-19 infection? And: How is the course of a COVID-19 infection among nursing home residents? This knowledge is important for the organization of care, policy considerations and the national distribution of protective materials. Registration is now possible via 5 different EPD (electronic medical record)- systems.

In addition, The living Labs have started a survey on the consequences of the pandemic for care staff in nursing homes and for informal caregivers of residents.

Finally, the Living Lab is involved in the development of a triage instrument for the rehabilitation of elderly AFTER a COVID-19 infection as well as in the development of treatment guidelines for the geriatric rehabilitation of elderly AFTER a COVID-19 infection.

For more information, please contact Hilde Verbeek. 

Rehabilitation COVID-19 patients

It is important to be able to provide appropriate support to every corona patient in order to return to an optimal level of functioning as soon as possible. In collaboration with the hospitals in the Limburg region, Adelante, Ciro, the Living Lab Rehabilitation and the Living Lab in Ageing and Long-Term Care South Limburg have joined forces to provide appropriate rehabilitation. Read more.

For more information, please contact prof. Jeanine Verbunt.

Covid-19 Reporting system for Dutch General Practitioners

All general practice departments at Dutch universities collaborate in a single large-scale project to establish the numbers of COVID-19 patients nationally who are receiving intensive and palliative care from GPs outside of hospital. The project is led by Jochen Cals, professor of Effective Diagnostics and General Practitioner. The General Practice Consortium shares the national results on its website on a regular basis. Read more.

For more information, please contact prof. Jochen Cals

Impact of COVID-19 on the Meuse-Rhine Euregion

MUMC+, GGD Zuid Limburg, euPrevent and Sciensano received a €1 million Interreg grant to investigate what the effects of the national prevention measures were and are on the occurrence of COVID-19 in the population of the Euregion Meuse-Rhine. In the coming year 30,000 people will be invited to take part in the study in two rounds.

Read more
For more information, please contact prof.dr. Christian Hoebe

Improvise, adapt, overwork? Understanding and learning from hospitals' adaptations to COVID-19 and their effects on professional functioning and recovery

Dirk Ruwaard, Daan Westra and their team received a ZonMw grant of €493.413 for their research project 'Improve, adapt, overwork? Understanding and learning from hospitals' adaptations to COVID-19 and their effects on professional functioning and recovery'. They will study the COVID-19 related adaptations by 5 hospitals in the Province of Limburg and their effects on the organisations and the wellbeing of their employees. The study aims to identify and disseminate best practices that help healthcare organizations throughout the country to successfully cope with the uncertainty of the crisis’ development.

Read more 
For more information, please contact prof.dr. Dirk Ruwaard

Primary care research on outcomes of COVID-19 (PRO-COVID-19)

Jochen Cals, Eefje de Bont and their team (RL Optimising Patient Care) have been awarded a ZonMw grant (€ 374.457) for their research project ‘Primary care Research on Outcomes of COVID-19 (PRO-COVID19’. They will study which patients suspected of COVID-19 who visited the GP, have an increased risk of of being admitted to hospital. The long-term consequences of more serious COVID-19 infections (complicated respiratory tract infections) of patients who have visited the GP are also being studied.

Read more
For more information, please contact dr. Eefje de Bont

Daily COVID-19 Evidence Update


Every day, the Clinical Epidemiology & Medical Technology Assessment (KEMTA) department makes an evidence update on COVID-19. This update helps policy makers and health professionals to keep up to date with the latest knowledge. Read more