Breaking news😮. A study shows that telomerase therapy does not increase the risk of cancer.
Gene therapy with telomerase is effective against diseases caused by excessive shortening of telomeres and aging.
Telomerase has always been associated with cellular immortality, given that telomerase is believed to be one of the pillars that support tumor growth.
The novelty is that they have now demonstrated through a 'killer experiment' (an experiment that creates the worst conditions for their hypothesis to be met) its efficacy and safety by applying this therapy to lung cells in mice that reproduced human lung cancer, therefore having a higher risk of developing this disease. The results were negative. This suggests that gene therapy with telomerase is safe even in a context of increased risk.
The Spanish group that discovered it is part of the CNIO (National Center for Oncological Research) led by María Blasco.
For more than 20 years, Blasco's work has focused on demonstrating the importance of telomeres and telomerase in cancer, as well as in age-related diseases.