Circulation and Breathing II

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In year 1, the physiology of the cardiopulmonary system has been studied. In year 3, chronic cardiopulmonary pathology will be discussed from a clinical perspective. Course 2.1 forms the bridge between year 1 and 3 by focusing on basic pathophysiology of cardiopulmonary diseases. The course is built around the major organ system involved: the heart, vasculature, kidneys and lungs. Each of these four parts starts with an introductory lecture on physiology, to refresh the knowledge about each organ system, and ends with a clinical lecture detailing how pathophysiological mechanisms affect patients and how this knowledge can guide treatment. The following diseases are discussed in tutorial groups: • The vasculature: atherosclerosis and myocardial infarction • The heart: arrhythmias, valvular disease and heart failure • The kidneys: renal artery stenosis and acid-base disorders • The lungs: asthma and pneumonia The course includes practica on hemodynamics, anatomy and histology, as well as 'skills lab' training on physical examination of cardiac function, pulmonary function and resuscitation. Each tutorial group will give a short presentation at a poster session about a variety of topics in pulmonary (patho)-physiology. In addition, a workshop on the design of randomized clinical trials will be organized. At the end of the course, we will focus on hypovolemic and septic shock, integrating the (dys)-regulation by the organ systems and the interactions within the cardiopulmonary system.