Full course description
In this course students have an opportunity to get acquainted with the discipline of cell biology. This discipline has been profiting from the development and improvements of recombinant DNA technology and is a driving force in fundamental and biomedical research. In this course students are challenged to discuss, at a detailed molecular level, different cellular and genetic processes that are the basis of life as we know it. The aim of the course is to familiarize students with further knowledge in the field of cell biology, which will enable them to better understand and appreciate the newest developments in this research area. Discussions will revolve around general cell biological topics such as the role of membranes, membrane transport of small molecules, the nuclear architecture, the organization of the genome, regulation of transcription and translation, protein trafficking, the cell cycle and maintenance of genomic integrity, programmed cell death and senescence. The last task, dealing with cancer, serves as an integration task; knowledge of the previous topics is required to appreciate what the consequences can be when a cell goes astray and the defence mechanisms of the body fail.
- To obtain insight in basic molecular genetic and cell biological processes in cells, tissues and organisms by leading the student through the origin of life, its differentiation and diversification, and deregulation of molecular processes leading to disease.
This course is designed to be taken in combination with SKI2077 Lab Skills: Cell Biology. Students wishing to take the Lab Skills should concurrently enroll in or have completed this course. Students wishing to take SCI2037 Cell Biology without taking the Lab Skills may do so.
SCI1009 Introduction to Biology. Students with substantial high school experience in biology (for an indication of the relevant topics, see SCI-B, p. vi-viii) can contact the coordinator to request a waiver.
- Alberts et al., Molecular Biology of the Cell, 6th edition, 2014.
- Sadava et al., Life, the science of biology, 10th edition, 2012.
- Scientific publications provided during the course.