Imaging Muscle Health
Full course description
Muscle health can be defined in many ways, but muscle function, muscle mass, strength, endurance/fatigue are all aspects that are highly important for muscle health. This course will focus on these aspects of muscle health using short, interactive lectures.
Furthermore, since different tests are available to assess each aspect of muscle function, the course contains three practical training sessions. Furthermore, three problem-based learning assignments will cover (clinically) relevant situations of changing muscle function, where students will need to apply their knowledge to the specific problem.
Lastly, a project will be performed in small groups, in which students will make a presentation including an instruction movie on a technique of choice to determine muscle function.
Knowledge and understanding
- Understand how muscle mass and - metabolism are influencing muscle health in terms of strength, endurance, power and fatigue
- Understand how these factors of muscle health can be determined (by imaging-based and functional testing)
- Know the basic principles of imaging techniques such as MRI and MRS
Applying knowledge and understanding
- Apply the acquired knowledge to situations of changing muscle health like ageing or disease
- Evaluating the applicability (pro/cons) of various methods of determining muscle health for a given question
- Explain a technique to investigate muscle health in a clear and comprehensive way by making an instruction video
- Read and evaluate a scientific manuscript (critical reading)
- Write a scientific report (scientific writing, searching literature)
- Review and comment on a scientific report written by a peer (reviewing)
- Search for relevant information and report to a group (PBL in tutorial groups)
- Knowledge about design of experiments/testing (research methods and design)
-Skeletal Muscle Structure, Function, and Plasticity, pp. 1-90 (RL Lieber., 3rd edition 2009). -Physiology and exercise physiology literature -Loon et al., J. Applied Physiology, 1999, 87(4), 1413-1420. -Macauley et al. Diurnal variation in skeletal muscle and liver glycogen in humans with normal health and Type 2 diabetes. Clin Sci (Lond). 2015. 128(10):707-713. ..and others..!