Full course description
Biochemistry is considered the mother of all Life Sciences. Understanding Biochemistry will facilitate learning of more specialised Life Sciences such as Molecular and Cell Biology. This course will present the essentials of Biochemistry during 6 lectures and 10 tutorials. We will cover the structures, functions and interactions of the biomacromolecules, including proteins, lipids, carbohydrates, DNA and RNA, which perform many of the activities associated with life. We will provide insight in the specificity and action of enzymes, the biocatalysts of the cell. Further, we will explain metabolic pathways that result in the generation of ATP, the major energy currency of the cell. Finally we will present recent biochemical understandings on genome editing that revolutionize treatment of diseases at the level of correcting mutated genes (gene therapy).
At the end of the course you will be able to:
- communicate fundamental principles governing structure, function and interactions of biological molecules to students encountering biochemistry for the first time.
- appreciate the science of biochemistry and its relevance to Health and Disease.
- recognise the roles of bio-macromolecules like proteins, lipids, polysaccharides and nucleotides in living cells in the context of diseases such as hyperventilation, thrombosis and atherosclerosis.
- identify, explain, and discuss the basic principles of enzyme catalysis and inhibition.
- enter advanced courses that require more detailed biochemistry knowledge, and to enroll into various Master programs in the life sciences.
- Berg, J.M., Tymoczko, J.L., Stryer, L. Biochemistry. (8th ed). W.H. Freeman. ISBN-10: 1-4641-2610-0; ISBN-13: 978-1-4641-2610-
- Garrett and Grisham. Biochemistry. (4th ed.). Thomson Brooks/Cole. ISBN101133108792 ISBN13 978-1133108795.