The course builds on the introductory electronics lab and is split into three, two-week long projects covering the following topic areas: • Digital electronics for computing: This project covers the basics of binary number systems, Boolean algebra, and logic devices. You will build a digital clock to provide an appreciation of how digital devices can perform different functions. A similar device will be built using the Arduino microcontroller to better understand how an integrated microcontroller can achieve the same functions of many discrete logic components. • Analogue electronics with bioengineering applications: In this project you will build an ECG generator and measurement unit using analogue components with the aim of better understanding analogue electronics and their potential applications in biomedical engineering. Students will gain a more detailed insight into the charging and discharging characteristics of biological and technological capacitors as well as understanding the function of amplifiers, filters and counters. • Electrochemical impedance measurement and biosensor technology Impedance spectroscopy is an electronic read-out technology which emerged in the Nazi era, used to investigate the structural quality of U-boats. Through the decades the technology was optimized and is now an established technology, implemented in (bio) medical research. It has been used for the detection of proteins, neurotransmitters and even the detection of single nucleotide polymorphisms in DNA sequences. In this project you will mimic this last experiment and try to delineate impedimetric signals in way that DNA melting times can be calculated and based on this information you will try to distinguish between a full matching DNA sequence and a mutated DNA sequence.
• To appreciate the theory behind digital (Boolean) logic and logic gate applications and to develop an insight into how computers function. • To design, study and build circuits involving adders, flip-flops, counters and sequential logic and understand how these devices can be used in everyday electronics. • To understand how an electrocardiogram (ECG) measures the heart’s electrical pulses and translates these into an analogue waveform. • To build an ECG generator and detector and collect measurements using these. • To use impedance spectroscopy to distinguish between different samples and understand the principles behind this technique.
MAT1001 Introduction to Natural Sciences: Calculus or PHY1002 Introduction to Natural Sciences: Mathematical Foundations of Physics PRA1006 Electronics