Methods and Analytics
Full course description
After graduation, you will have to translate and communicate industrial- and consumer relevant questions into innovative scientific research questions, and interpret scientific results for the benefit of product development. This requires thorough insight in the skills, which are needed to design, conduct and understand biomedical experiments. Accordingly, this course is designed to train you in the methodology of scientific studies, and provide you with knowledge on a number of analytical techniques and practical skills, which are essential to conduct scientific intervention trials for the substantiation of product benefit claims. A broad view with specific attention to dedicated in vivo, ex vivo and in vitro technologies will be offered. Special attention will be given to epidemiological research. Epidemiology is an important scientific discipline, especially in an industrial setting, where often the methodology and facilities are lacking to conduct small- scale interventions. In this course, specific attention will be paid to descriptive epidemiology, and to skill development to find, critically read and judge the quality of epidemiological literature. Throughout this course, knowledge on several life science technology aspects, which are widely in use in the interface between food industry and health and nutrition science, will be obtained during laboratory sessions at the specialised laboratory facility at the FHML facility in Maastricht. Biomedical analysis techniques, using a variety of biochemical assays on different samples will be demonstrated in the lab. All activities will be supported by problem cases, which will be discussed in Problem Based Learning groups. On each of the different topics which are covered, lectures will be provided by academic staff. Scientists working in an industrial setting will provide lectures to show the application of the diverse techniques in food industry.
- Comprehension of the etiology of- and patho-biological theories of chronic metabolic disorders in which lifestyle and diet play a significant role, especially obesity, diabetes, cardiovascular disease and irritable bowel syndrome
- Comprehension of the role of epidemiology in assessing "Diet- Health" relationships
- Insights in emerging technologies that impact on the food production process and the opportunities for innovation in the area of food composition, taste, texture and mouth-feel
- Understanding public health and risk/benefit assessment (incl. toxicology aspects)
- Knowledge about relevant biomedical analytics and technologies such as body composition analysis, stable isotope methods, in vitro digestion models, cell line models, transcriptomics, proteomics and systems biology, sensory test models
- Insight in clinical trial design and its role related to impact on the degree of health benefit evidence
- Insight in the design and role of meta-analysis;
- Original recent research articles that will be referred to in the course book
- Original research articles and reviews on relevant topics, to be collected on own initiative, according to training 'how to find and interpret scientific literature'.
- F.H.M. van Osch