The emphasis of this course will be on a number of essential topics in analytical sciences and related to modern bio- and polymer chemistry, chemical- and biotechnological engineering. As a start, the course will touch on the basic physical chemical properties of molecules in different phases. The translation of these properties to the capability of modern separation and detection technologies will be made. In the final part, of the course focuses on the so-called hyphenation of the analytical technologies and their application in chemical and biological sciences, together with the basics of analytical statistics and method development. Typical topics in the course are based on the quantification and molecular structure assessment of chemical, biological relevant metabolites, bio- and synthetic polymers.
• To gain an understanding of physical chemical properties of molecules in the liquid-, super critical- and gas-phase. • To recognize various separation technologies and correlate the "physical chemical properties of molecules to the "mode of action" in gas- and liquid chromatography. • To obtain an understanding of the physical chemistry fundaments in spectroscopic technologies, including UV/VIS, IR/Raman, MS and NMR. • Create a fundamental understanding in "sampling, sample storage and sample pre-treatment" together with the basics of statistical methodologies. • To gain insight in "Process Analytical Technologies" applied by in-, at and on-line detection technologies, regulatory requirements. • To become familiar with quantification and molecular structure analysis of chemicals, metabolites, bio- and synthetic polymers using hyphenated technologies, e.g. liquid chromatography with flow-NMR. • Obtain insight into different applications of analytical methodologies and acquire sufficient background for more advanced courses in polymer-, bio-chemistry and life sciences.